Neuroscience Studies

Mentha spp. Essential Oils: A Potential Toxic Fumigant with Inhibition of Acetylcholinesterase Activity on Reticulitermes dabieshanensis.

Essential oils from plants with linalool, menthol, and carvone were found to be effective against termites. When combined, their insecticidal potency increases, making them a potential alternative to synthetic insecticides for termite control.

Wu Z et al (2023).
Plants (Basel).
PubMed:
38068668

Exploring the interaction of phytochemicals from Hibiscus rosa-sinensis flowers with glucosidase and acetylcholinesterase: An integrated in vitro and in silico approach.

Hibiscus rosa-sinensis flowers extract (HRA) was prepared and shown to have antioxidant activity. HRA inhibited glucosidases and AChE activity, potentially useful for diabetes and cognitive improvement. The active constituents CS and QS stably bind to target proteins.

Loganathan C et al (2023).
Comput Biol Chem.
PubMed:
38061170

Protective and therapeutic effects of okra seed in acute nontraumatic brain injury.

This study investigated the effects of okra seed extract on liver damage and brain injury caused by acetaminophen. Okra has antioxidant and anti-inflammatory properties, making it potentially useful for protection and treatment.

Yoldaş MA et al (2023).
Int J Neurosci.
PubMed:
38060590

New Lycopodium alkaloids with neuroprotective activities from Lycopodium japonicum Thunb.

Researchers isolated a new lycopodine-type alkaloid from Thunb plants. This alkaloid and others showed potential neuroprotective and anti-apoptotic effects, which could be relevant for developing treatments for brain damage.

Xie Z et al (2023).
Nat Prod Res.
PubMed:
38058102

Ethanol extract of Andrographis paniculata alleviates aluminum-induced neurotoxicity and cognitive impairment through regulating the p62-keap1-Nrf2 pathway.

This study explores the potential neuroprotective effects of Andrographis paniculata (AP) in an aluminum-induced model of Alzheimer's disease (AD). AP reduces cognitive impairments, amyloid-β protein deposition, and activates autophagy through the p62-Keap1-Nrf2 pathway, suggesting its potential as a therapeutic intervention.

Ma J et al (2023).
BMC Complement Med Ther.
PubMed:
38057817

Clerodane diterpenoids with in-vitro anti-neuroinflammatory activity from the tuberous root of Tinospora sagittata (Menispermaceae).

Researchers have isolated 26 diterpenoids from a Chinese medicinal plant. One compound is a new type of diterpenoid with a unique ring structure. Three compounds show promising anti-inflammatory activity, potentially useful for treating conditions involving excessive inflammation.

Song JQ et al (2023).
Phytochemistry.
PubMed:
38056516

Mechanisms for the biological activity of Gastrodia elata Blume and its constituents: A comprehensive review on sedative-hypnotic, and antidepressant properties.

Researchers studied Gastrodia elata Blume (a Chinese herbal medicine) and its effects on insomnia and depressive symptoms. It was found to have sedative-hypnotic and antidepressant effects, suggesting it could be a potential treatment option with fewer side effects.

Zhou HB et al (2023).
Phytomedicine.
PubMed:
38056151

Ethanol extract of Verbena officinalis alleviates MCAO-induced ischaemic stroke by inhibiting IL17A pathway-regulated neuroinflammation.

Researchers investigated the therapeutic potential of Verbena officinalis in managing ischaemic stroke. Significant neuroprotective effects were observed, but further research is needed to understand the bioactive compounds and mechanisms involved. This study may offer insights for developing new treatment strategies.

Zhang W et al (2023).
Phytomedicine.
PubMed:
38056148