Neuroscience Studies

Clinical effectiveness of pharmacological and non-pharmacological treatments for the management of anxiety in community dwelling people living with dementia: A systematic review and meta-analysis.

Music therapy, cognitive activities, and non-drug interventions effectively reduce anxiety in dementia patients. Ginkgo biloba, probiotics, olanzapine, loxapine, and citalopram may also show promise in managing anxiety.

Nimmons D et al (2023).
Neurosci Biobehav Rev.
PubMed:
38097097

Neuroprotective effect of the traditional decoction Tian-Si-Yin against Alzheimer's disease via suppression of neuroinflammation.

Researchers investigated the therapeutic potential of the herbal decoction Tian-Si-Yin for Alzheimer's disease (AD). Tian-Si-Yin, a traditional Chinese medicine, has been used for dementia and neurological conditions. Its effectiveness for AD and its mechanisms are not yet fully understood.

Zhou L et al (2023).
J Ethnopharmacol.
PubMed:
38086513

Two new constituents from the endophyte of Alternaria alternata and its anti-neuroinflammatory activity guided by molecular docking.

New compounds and known compounds obtained from an endophyte isolated from [unnamed source]. Structures confirmed through spectroscopic analyses and molecular docking. Compounds 1 and 3 show anti-neuroinflammatory activity in microglial cells. Potential for treatment of neuroinflammatory-related diseases.

Yang X et al (2023).
Nat Prod Res.
PubMed:
38084022

Polysaccharide from Polygala tenuifolia alleviates cognitive decline in Alzheimer's disease mice by alleviating Aβ damage and targeting the ERK pathway.

Polygala tenuifolia, a key herb in Chinese medicine for treating dementia, contains polysaccharides. Understanding the role and effects of these compounds can help make better decisions for dementia treatment and research in the lab.

Li Y et al (2023).
J Ethnopharmacol.
PubMed:
38081400

Activity of Citrus aurantium and Lavandula angustifolia in Alzheimer's Disease Symptoms in Male Wistar Rats.

This study investigated the effects of hydro-alcoholic extracts on Alzheimer's Disease (AD) and antioxidant problems. It provides insights into potential treatments for AD, which could be relevant for your lab's research on neurodegenerative disorders.

Arasteh A et al (2023).
Avicenna J Med Biotechnol.
PubMed:
38078339

Codonopsis pilosula polysaccharide alleviates rotenone-induced murine brain organoids death through downregulation of gene body DNA methylation modification in the ZIC4/PGM5/CAMTA1 axis.

Codonopsis pilosula polysaccharide (CpP) protected mouse brain organoids from rotenone damage by reducing cytotoxicity and promoting cell cycle progression through demethylation modifications.

Chen H et al (2023).
Biochem Biophys Rep.
PubMed:
38074999

Effects of inhalation of peppermint oil after lumbar discectomy surgery on pain and anxiety levels of patients: A randomized controlled study.

Study showed inhaling peppermint oil post-surgery reduces pain and anxiety. Use in post-operative care for better patient outcomes.

Meşe M and Sarıtaş S (2024).
Explore (NY).
PubMed:
38072763