Neuroscience Studies

Da-Chuan-Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA-Salt Hypertensive Rats.

DCXD, a Chinese herbal extract, is traditionally used to treat cardiovascular disease. This study explores its potential to lower blood pressure in hypertension and the mechanisms involved.

Zhang Q et al (2024).
Int J Hypertens.
PubMed:
38344148

Saffron (Crocus sativus L.) extract attenuates chronic scopolamine-induced cognitive impairment, amyloid beta, and neurofibrillary tangles accumulation in rats.

Saffron, a popular food condiment, has various health benefits, including immune boosting, aphrodisiac, and liver protective properties. It is also known to have positive effects on mood and neurodegenerative disorders like dementia and Parkinson's.

Patel KS et al (2024).
J Ethnopharmacol.
PubMed:
38341114

Extracts of Sideritis scardica and Clinopodium vulgare Alleviate Cognitive Impairments in Scopolamine-Induced Rat Dementia.

Griseb. and L. extracts improved memory and preserved monoaminergic function in rats. Griseb. helped with spatial working memory, while L. showed antioxidant and acetylcholinesterase inhibitory activity. The extracts also protected against impairments. More research is needed for therapeutic use.

Lazarova M et al (2024).
Int J Mol Sci.
PubMed:
38339117

Chronic Treatment with Nigella sativa Oil Exerts Antimanic Properties and Reduces Brain Inflammation in Rats.

Researchers studied the effects of chronic consumption of a herb called NS on manic-like behavior in rats. They found that NS had a significant antimanic-like effect and also positively modulated certain inflammatory mediators. This suggests that NS may have therapeutic benefits for mental illness.

Uzzan S et al (2024).
Int J Mol Sci.
PubMed:
38339101

Nutraceuticals and Pain Disorders of the Gut-Brain Interaction in Infants and Children: A Narrative Review and Practical Insights.

Researchers reviewed studies on nutraceuticals for infants and children with abdominal pain and gut-brain disorders. They found that fennel, herbal extracts, DSM 17938, BB-12, peppermint oil, psyllium fibers, corn fiber cookies, guar gum, and vitamin D showed potential in reducing pain. However, more research is needed to confirm their efficacy and safety.

Salvatore S et al (2024).
Nutrients.
PubMed:
38337634

Neuroprotective effects of Embelin in an ethidium bromide-induced multiple sclerosis in rats: Modulation of p38 MAPK signaling pathway.

Researchers studied the effects of embelin on the p38 MAPK pathway in a mouse model of MS. Embelin showed potential as a therapeutic agent for MS due to its anti-inflammatory properties.

Anika, Singh S and Rimpi (2024).
Int Immunopharmacol.
PubMed:
38335654

Antidepressant effects of Parishin C in chronic social defeat stress-induced depressive mice.

Researchers investigated the effects of Parishin C, a compound found in Gastrodia elata Blume plant, on depression. It is safe and has neuroprotective properties. Its potential benefits for depression need further exploration.

Jiang N et al (2024).
J Ethnopharmacol.
PubMed:
38331122

Evaluation of the biological efficiency of Terminalia chebula fruit extract against neurochemical changes induced in brain of diabetic rats: an epigenetic study.

The study found that the ethanolic Terminalia chebula extract reduced oxidative stress, improved brain integrity, and decreased abnormal changes in the brains of diabetic rats. This suggests that T. chebula extract could potentially be beneficial for the treatment of diabetes-related neuroinflammation.

El-Shamarka MEA et al (2024).
Inflammopharmacology.
PubMed:
38329710