Neuroscience Studies

The effect of Annona muricata (Graviola) on the prevention of brain damage due to ionizing radiation in rats.

Ethanol extract of AM leaves may protect against brain damage from ionizing radiation in rats. AM decreased astrocyte and microglial reactions, inflammation, and edema compared to IR alone. AM reduced oxidative damage caused by IR.

Elmas O et al (2024).
Heliyon.
PubMed:
38370260

Protective effect of Danshensu against neurotoxicity induced by monosodium glutamate in adult mice and their offspring.

Danshensu (DSS) protects against monosodium glutamate (MSG)-induced neurotoxicity in adult mice and their offspring. It prevents brain damage, improves learning and memory, and reduces neural overexcitation.

Liang Q et al (2024).
Heliyon.
PubMed:
38356496

Nelumbo nucifera leaves extract ameliorated scopolamine-induced cognition impairment via enhanced adult hippocampus neurogenesis.

N. nucifera leaf extracts and Q3G improved cognition and reduced apoptosis in scopolamine-induced cognitive impairment by regulating the BDNF signaling pathway and promoting neurogenesis in the hippocampus. Important for lab decisions.

Lee YJ et al (2024).
Environ Toxicol.
PubMed:
38351887

Mechanistic study of the anti-excitatory amino acid toxicity of Bushen Zhichan decoction for Parkinson's disease based on the transcriptional regulation of EAAT1 by YY1.

Bushen Zhichan decoction (BSZCF) is a traditional Chinese herbal formula derived from Liuwei Dihuang Pill. It is used to treat Parkinson's disease by nourishing and tonifying the liver and kidneys. More research is needed to understand how it works.

Liu L, Tian X and Li W (2024).
J Ethnopharmacol.
PubMed:
38350506

COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice.

COP-22, a curcumin derivative, shows potential in protecting the brain from aging-induced damage by reducing oxidative stress, improving cholinergic system dysfunction, and protecting nerve cells. It also demonstrates the ability to reduce oxidative stress in the liver and kidney. It could be used in aging therapy and to treat diseases like Alzheimer's.

Ma Y et al (2024).
Mol Neurobiol.
PubMed:
38347285

Multi-target drugs for the treatment of cognitive impairment and fatigue in post-COVID syndrome: focus on Ginkgo biloba and Rhodiola rosea.

Post-COVID syndrome leads to cognitive impairment, depression, and fatigue due to neuroinflammation, oxidative stress, and mitochondrial dysfunction. Herbal drugs like Ginkgo biloba and Rhodiola rosea may improve cognition, reduce fatigue and depression, but more research is required.

Mueller JK and Müller WE (2024).
J Neural Transm (Vienna).
PubMed:
38347175

Anji white tea relaxes precontracted arteries, represses voltage-gated Ca(2+) channels and voltage-gated K(+) channels in the arterial smooth muscle cells: Comparison with green tea main component (-)-epigallocatechin gallate.

Researchers studied the vascular effects of Anji white tea, a popular green tea rich in EGCG, to better understand its potential benefits for cardiovascular health.

Xu X et al (2024).
J Ethnopharmacol.
PubMed:
38346524

Nigella sativa oil exhibits anti-aging effects in transgenic Alzheimer's Drosophila melanogaster via anti oxidant pathways: survival-rate and life span studies.

This study investigated the anti-aging effect of oil on transgenic flies. Results show that low-dose NSO increased the lifespan of AB-42 treated flies. Care because it suggests the efficacy of NSO in increasing survival and lifespan.

Mukhtar AI, Danborno B and Sadeeq AA (2024).
Toxicol Res (Camb).
PubMed:
38344667