Icariin improves learning and memory function in Aβ(1-42)-induced AD mice through regulation of the BDNF-TrκB signaling pathway.

Wan M et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117029

PubMed:

37579923

Neuroprotective Effects of Tinospora cordifolia via Reducing the Oxidative Stress and Mitochondrial Dysfunction against Rotenone-Induced PD Mice.

TCE extract protected against Parkinson's disease in mice by reducing oxidative stress, improving mitochondrial function, and reducing cell death. TCE could have potential as a neuroprotective treatment for Parkinson's disease.

Dilnashin H et al (2023).

ACS Chem Neurosci.

DOI:

10.1021/acschemneuro.3c00216

PubMed:

37579290

Evaluation of the Effect of Barberry Root (Berberis Vulgaris) on the Prevention of Metabolic Syndrome Caused by Atypical Antipsychotic Drugs in Patients with Schizophrenia: A Three-Blind Placebo-Controlled Clinical Trial.

This study aimed to investigate the potential of barberry root extract in preventing metabolic syndrome caused by antipsychotic drugs in patients with schizophrenia. However, the results showed that the extract was not effective in controlling the effects of these drugs on metabolic syndrome.

Rostami H et al (2023).

Iran J Psychiatry.

DOI:

10.18502/ijps.v18i3.13015

PubMed:

37575603

Neurovascular glial unit: A target of phytotherapy for cognitive impairments.

Herbal medicines may be useful for treating cognitive impairment in Alzheimer's disease and vascular dementia, by targeting dysfunction in the neurovascular glial unit.

Chen L et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155009

PubMed:

37573807

The Effects of Andrographis paniculata (Burm.F.) Wall. Ex Nees and Andrographolide on Neuroinflammation in the Treatment of Neurodegenerative Diseases.

This review discusses the potential of the natural compound Ap and its constituent Andro in modulating neurodegeneration and neuroinflammation, which are major causes of neurodegenerative diseases.

Bosco F et al (2023).

Nutrients.

DOI:

10.3390/nu15153428

PubMed:

37571363

Phytochemical Profiling, Antioxidant and Cognitive-Enhancing Effect of Helichrysum italicum ssp. italicum (Roth) G. Don (Asteraceae).

This study found that the methanol-aqueous extract from ssp. aerial parts has antioxidant properties and can improve memory and learning. It contains various compounds that can enhance cognitive function.

Gevrenova R et al (2023).

Plants (Basel).

DOI:

10.3390/plants12152755

PubMed:

37570911

Asiaticoside Mitigates Alzheimer's Disease Pathology by Attenuating Inflammation and Enhancing Synaptic Function.

Asiaticoside (AS) reduced cognitive dysfunction and neuroinflammation in AD mice by inhibiting microglia activation and the p38 MAPK pathway, suggesting AS as a potential AD treatment.

Liu S et al (2023).

Int J Mol Sci.

DOI:

10.3390/ijms241511976

PubMed:

37569347

Saffron and crocin ameliorate prenatal valproic acid-induced autistic-like behaviors and brain oxidative stress in the male offspring rats.

This study examined the effects of saffron and its active ingredient, crocin, on an animal model of autism. Results showed that saffron and crocin reduced behavioral abnormalities and oxidative stress in the brain. These findings suggest that saffron and crocin could be potential treatments for autism. However, more research is needed to confirm their efficacy.

Seyedinia SA et al (2023).

Metab Brain Dis.

DOI:

10.1007/s11011-023-01275-7

PubMed:

37566156