Neuroscience Studies

Investigating Cannabidiol's potential as a supplementary treatment for schizophrenia: A narrative review.

CBD may be a safer and effective adjunctive therapy for schizophrenia, with antipsychotic, anxiolytic, and neuroprotective effects. Research is needed to fully understand its potential benefits and interactions with traditional antipsychotics.

Denis Völker JS, Micluția IV and Vinași RC (2024).
Eur J Pharmacol.
PubMed:
39068976

Genus Sambucus: Exploring Its Potential as a Functional Food Ingredient with Neuroprotective Properties Mediated by Antioxidant and Anti-Inflammatory Mechanisms.

Review on neuroprotective properties of and its compounds, including antioxidant, anti-inflammatory, and neuroregenerative effects. Benefits in Alzheimer's and Parkinson's models due to polyphenols like anthocyanins. Potential as functional food ingredient discussed. Valuable insights for brain health strategies.

Merecz-Sadowska A et al (2024).
Int J Mol Sci.
PubMed:
39063085

Antioxidant and Anti-Apoptotic Neuroprotective Effects of Cinnamon in Imiquimod-Induced Lupus.

Study investigated cinnamomum cassia for antioxidant potential in lupus redox pathways. Potential novel therapy for lupus due to antioxidant properties, may impact disease activity.

Maalouly G et al (2024).
Antioxidants (Basel).
PubMed:
39061948

Antioxidant and Neuroprotective Effects of Seed Oils from Trichosanthes kirilowii and T. laceribractea in Caenorhabditis elegans: A Comparative Analysis and Mechanism Study.

Seed oils from Maxim and Hayata seeds have strong antioxidant and neuroprotective effects, reducing ROS levels and preventing amyloid β and tau protein aggregation in neuron cells. This research could lead to potential therapies for neurodegenerative diseases like Alzheimer's.

Wang W et al (2024).
Antioxidants (Basel).
PubMed:
39061929

Neuroprotective properties of the Lilium brownii extracts in the experimental model of Parkinson's disease.

L. brownii extracts improve motor dysfunction, increase neuron count, reduce oxidative stress, and modulate p62-Keap1-Nrf2 pathway in PD mice. Ethanol extract more effective due to higher phenolic acid glyceride content.

Hui C et al (2024).
Metab Brain Dis.
PubMed:
39060803

Pereskia sacharosa Griseb. (Cactaceae) Prevents Lipopolysaccharide-Induced Neuroinflammation in Rodents via Down-Regulating TLR4/CD14 Pathway and GABAA γ2 Activity.

Researchers analyzed Griseb. plant leaves for phenolic content and tested anti-inflammatory properties on animals with neuroinflammation. Results show compounds cross the BBB, reduce inflammation markers, and improve activity levels. This could lead to new treatments for inflammation-related conditions.

Prado-Fernández MF et al (2024).
Curr Issues Mol Biol.
PubMed:
39057053