Diabetes Studies

Roselle Calyx (Hibiscus Sabdariffa. L) Ethyl Acetate Fraction Lowering MDA, TNF-α and Reduce Hypercoagulability in Diabetic Model.

Study on ethyl acetate fraction of Hibiscus calyxes in diabetic rats showed decreased MDA and TNF-α levels, improved bleeding time, and platelet count. Suggests potential for managing diabetes-related complications, relevant for lab research.

Abdillah R et al (2024).
Pharmacology.
PubMed:
38583417

Effects of garlic (Allium sativum L) and Citrullus colocynthis (L.) Schrad individually and in combination on male reproductive damage due to diabetes: suppression of the AGEs/RAGE/Nox-4 signaling pathway.

Garlic and Citrullus colocynthis improve male reproductive function in diabetes through antioxidant properties. Lowering doses may still be effective in achieving desired results without unwanted side effects.

Mohammadzadeh A, Gol A and Kheirandish R (2024).
BMC Complement Med Ther.
PubMed:
38581015

Chinese herbal medicine decreases incidence of hepatocellular carcinoma in diabetes mellitus patients with regular insulin management.

Abstract: Type 2 DM increases risk of HCC due to insulin's pro-cancer effects. Finding preventative therapy for insulin users is crucial for researchers.

Lai HC et al (2024).
World J Gastrointest Oncol.
PubMed:
38577471

PPAR gamma agonistic activity of dillapiole: protective effects against diabetic nephropathy.

Dillapiole, a component of essential oils, acts as a PPARγ agonist, improving glucose levels and lipid profiles in diabetic mice. Promising potential for further research on diabetes treatment.

Shafi S, Khurana N and Gupta J (2024).
Nat Prod Res.
PubMed:
38563125

Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models.

Study tested ZJ and EA extracts on diabetic rats, showed cognitive improvement in Morris water maze test. Potential cognitive enhancers and hypoglycemic agents in diabetes management.

Annepaka ER et al (2024).
Cureus.
PubMed:
38562322

Protein hydrolysates of Moringa oleifera seed: Antioxidant and antihyperglycaemic potential as ingredient for the management of type-2 diabetes.

New plant proteins hydrolyzed with proteases show high antioxidant and glucose uptake properties. Ideal for functional foods targeting type-2 diabetes management. Valuable for developing nutritional therapies.

Bakwo Bassogog CB et al (2024).
Heliyon.
PubMed:
38560105

Green Synthesis of Zinc Oxide Nanoparticles from Althaea officinalis Flower Extract Coated with Chitosan for Potential Healing Effects on Diabetic Wounds by Inhibiting TNF-α and IL-6/IL-1β Signaling Pathways.

Researchers developed eco-friendly wound healing formulations using ZnO-NPs and chitosan gel with antioxidant and antibacterial properties. This could help diabetic patients with chronic wounds heal faster and prevent complications like ulcers and gangrene.

Elhabal SF et al (2024).
Int J Nanomedicine.
PubMed:
38559447

A fast and efficient method for screening and evaluation of hypoglycemic ingredients of Traditional Chinese Medicine acting on PTP1B by capillary electrophoresis.

Inhibitors of PTP1B, an enzyme involved in insulin signaling and diabetes, were screened using CE. Traditional Chinese Medicine showed strong inhibition, with fast analysis time, making it a valuable tool for drug discovery.

Gao J et al (2024).
J Pharm Biomed Anal.
PubMed:
38554553