Hypolipidemic, Hypoglycemic, and Ameliorative Effects of Boiled Parsley (Petroselinum crispum) and Mallow (Corchorus olitorius) Leaf Extracts in High-Fat Diet-Fed Rats.

Boiling parsley and mallow extracts increases their antioxidant activity. When given to rats on a high-fat diet, the boiled herb extracts reduced body weight, cholesterol, and triglycerides, while increasing HDL cholesterol levels. Boiling parsley is suggested to combat obesity.

Almutairi AA et al (2023).

Foods.

DOI:

10.3390/foods12234303

PubMed:

38231757

In-vivo anti-hyperglycemic effect of herbal extracts Tribulus terrestris (L) and Curcuma amada (R) on streptozotocin-induced diabetic rats and its associated histopathological studies.

This study found that a combined herbal extract of TT and CA effectively reduced blood glucose levels, increased insulin and glycogen levels, and decreased HbA1c, urea, and creatinine levels in diabetic rats. The extract could be a potential natural antidiabetic agent.

Kaliaperumal K et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e24009

PubMed:

38230238

Validation of Blood Glucose and Lipid-Lowering Effect of Solvent Fractions of the Crinum Abyssinicum Shoot Tips in Streptozotocin-Induced Diabetic Mice.

A study examined the therapeutic potential of crushed shoot tips of Amaryllidaceae for diabetes. The traditional practice in Ethiopia lacks scientific support, so understanding its effectiveness is crucial for exploring new treatments.

Tegegne BA et al (2024).

Glob Adv Integr Med Health.

DOI:

10.1177/27536130231225464

PubMed:

38226326

Phytochemical Analysis, acetylcholinesterase inhibition, antidiabetic and antioxidant activity of Atriplex halimus L. (Amaranthaceae Juss.).

Mediterranean saltbush contains beneficial compounds like phenols and flavonoids, which have antioxidant properties. These compounds also have potential health benefits against diabetes and acetylcholinesterase-related conditions. Enzyme activities are linked to the presence of terpenes, sterols, saponins, coumarins, and carotenoids.

Mkaddem Guedri M et al (2024).

Chem Biodivers.

DOI:

10.1002/cbdv.202301941

PubMed:

38224199

Response surface methodology based development of an optimized polyherbal formulation and evaluation of its anti-diabetic and anti-obesity potential in high-fat diet-induced obese mice.

Researchers created a mix of edible seeds to test its effect on diabetes and obesity in mice. The results could potentially help develop a new treatment for these conditions.

Tanisha, Venkategowda S and Majumdar M (2023).

J Tradit Complement Med.

DOI:

10.1016/j.jtcme.2023.07.002

PubMed:

38223811

Natural diterpenoid EKO activates deubiqutinase ATXN3 to preserve vascular endothelial integrity and alleviate diabetic retinopathy through c-fos/focal adhesion axis.

EKO, a compound in Pteris semipinnata L., protects against vascular endothelial injury in diabetic retinopathy. It improves focal adhesion pathway and mitochondrial function, promising therapeutic potential.

Ge D et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.129341

PubMed:

38218272

Corn stigma ameliorates hyperglycemia in zebrafish and GK rats of type 2 diabetes.

Liang H et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117746

PubMed:

38216098

Insights into the mechanisms of diabetic wounds: pathophysiology, molecular targets, and treatment strategies through conventional and alternative therapies.

Plants and their active constituents can potentially treat diabetic foot syndrome, promoting wound healing, reducing inflammation, and stimulating angiogenesis. These alternatives could decrease amputations and offer affordable options. Further research is needed for a better understanding.

Yadav JP et al (2024).

Inflammopharmacology.

DOI:

10.1007/s10787-023-01407-6

PubMed:

38212535