Diabetes Studies

Wild Rosa roxburghii Tratt Juices Grown at Different Altitudes Regulate Blood Glucose in Type 1 Diabetic Mice via the PI3K/Akt Pathway.

Wild RRT juice from different altitudes improved glucose and lipid metabolism disorders and oxidative damage in type 1 diabetes mellitus (T1DM) mice, possibly due to activation of the PI3K/Akt pathway. The most effective group was medium altitude.

Diabetes Rosa roxburghii
Zhu Y et al (2023).
J Med Food.
DOI:
10.1089/jmf.2023.K.0118
PubMed:
37890111

Anti-Diabetic Effects of the 80% Methanolic Extract of Datura Stramonium Linn (Solanaceae) Leaves in Streptozotocin- Induced Diabetic Mice.

Researchers investigated the anti-diabetic effects of Solanaceae leaves extract in diabetic mice and found it to be effective. This could lead to the development of affordable, plant-based medications with fewer side effects for managing diabetes.

Diabetes Datura stramonium
Baylie T et al (2023).
J Exp Pharmacol.
DOI:
10.2147/JEP.S426925
PubMed:
37873553

Toxicological Assessment and Anti-diabetic Effects of Combined Extract of Chirata, Fenugreek and Sesame on Regulating TNF-α, TGF-β and Oxidative Stress in Streptozotocin Induced Diabetic Rats.

Researchers investigated the potential of Swertia chirayita, Trigonella foenum-gracum, and Sesamum indicum in treating diabetes. Understanding the role of innate immunity and inflammation in diabetes-related microvascular problems is crucial.

DiabetesImmunology Swertia chirayitaTrigonella foenum
Shivam and Gupta AK (2023).
Curr Drug Discov Technol.
DOI:
10.2174/0115701638252203230919092315
PubMed:
37870057

Metabolomics and molecular networking approach for exploring the anti-diabetic activity of medicinal plants.

Researchers analyzed four medicinal plants and found that Plant A's methanol extract was most effective against α-amylase, while Plant B's water fraction showed strong α-glucosidase inhibition. Metabolic profiling revealed 32 secondary metabolites, with 22 tentatively identified.

Diabetes Terminalia chebula
Timilsina AP et al (2023).
RSC Adv.
DOI:
10.1039/d3ra04037b
PubMed:
37869390

The Potential Hepatoprotective Effect of Vaccinium arctostaphylos L. Fruit Extract in Diabetic Rat.

Researchers investigated the effects of arctostaphylos fruit extract on diabetic rats' livers. Understanding its molecular mechanisms could help enhance the treatment of diabetes.

Diabetes Vaccinium arctostaphylos
Saliani N, Montasser Kouhsari S and Izad M (2023).
Cell J.
DOI:
10.22074/cellj.2023.2004742.1328
PubMed:
37865880

Protective effects and mechanisms of Momordica charantia polysaccharide on early-stage diabetic retinopathy in type 1 diabetes.

This study found that Momordica charantia polysaccharide (MCP) can potentially prevent and alleviate diabetes mellitus (DM) and diabetic retinopathy (DR) by improving body weight, inflammation, and apoptosis in retinal tissues. MCP may be a promising medication for DM and a natural medicine for DR.

Diabetes Momordica charantia
Liu J et al (2023).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2023.115726
PubMed:
37862973

Gastroprotective evaluation of Medicago sativa L. (Fabaceae) on diabetic rats.

This study found that the ethanol extract of Alfalfa (EEMS) decreased ulcer index and free acidity in diabetic rats, showing anti-ulcer and liver/kidney protective effects. EEMS may be a potential treatment for stomach ulcers in diabetic patients.

Diabetes Medicago sativa
Chandra P et al (2023).
Saudi Pharm J.
DOI:
10.1016/j.jsps.2023.101815
PubMed:
37860685

A randomized, controlled, comparative, proof-of-concept study to evaluate the efficacy and safety of Nisha-Amalaki capsules in prediabetic patients for preventing progression to diabetes.

Combining Nisha and Amalaki can potentially prevent the progression from prediabetes to diabetes. You should care because it offers a natural and effective treatment option for early-stage diabetes.

Diabetes Curcuma longa
Munshi R et al (2023).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2023.100806
PubMed:
37857033
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