30 dopamine-derived betalains were discovered, characterized, and found to have unique properties. Higher hydrophobicity and different retention times than traditional betalains. Found in various plants, particularly abundant in quinoa. Essential phytochemicals in Caryophyllales.
Researchers identified active compounds in Hedyotis diffusa for Alzheimer's disease treatment using network pharmacology and molecular docking. Results suggest HD may inhibit Aβ, suppress AChE activity, and reduce oxidative stress. Care about potential new treatment options for AD.
Saffron contains safranal, which may help prevent seizures by reducing cell death and inflammation. Understanding this mechanism could lead to new epilepsy treatments.
Notoginseng leaf triterpenes enhance angiogenesis after stroke by activating Nrf2 and AMPK/SIRT1 pathways, promoting neuroprotection and neuronal regeneration. Potential future stroke treatment.
Researchers studied the effects of Acorus tatarinowii oils on microglial inflammation after ischemic stroke. Results showed AT oils reduced cerebral damage, inflammation, and improved gut microbiota balance. Gut microbiota played a crucial role in the protective effects of AT oils.
Study compared antidepressant efficacy of cyclodextrin-complexed nano-NS oleoresin with NS ethanolic extract in a murine model of depression. Nano-NSOR showed higher drug release and more pronounced antidepressant effect. Offers promising alternative with potential for improved treatment of depression.
Tongbian TCM helps with constipation by regulating water transfer in the colon through AQP3. Contains unique herbs like Atractylodes macrocephala and Astragalus membranaceus. Important for treating slow transit constipation.
Bacopa monnieri and Centella asiatica share neuroprotective mechanisms, supported by metabolomics and protein target prediction. Potential for memory enhancement and ROS reduction.