Researchers investigated the effects of a new compound on cancer cells. Results show potential for novel treatment options. Relevant for developing therapies in cancer research.
Chuanxiong extract improves cognitive function in a VaD model by inhibiting astrocyte and microglia activation. Shows potential for treating cerebrovascular diseases. Mitigates MAPK signaling changes.
The edible fern extract showed synergistic effects with donepezil against key enzymes in Alzheimer's disease pathogenesis, improving eye phenotypes in a model of AD without genotoxic effects. This combination therapy may reduce adverse side effects of AD drugs.
Researchers isolated steroidal saponins from a wild eggplant relative. These compounds may have anti-inflammatory, sedative, and anti-epileptic effects. They do not show antiproliferative or hepatotoxic effects. This could lead to new natural therapies.
Researchers studied the effects of fruit extract on stress and anxiety in zebrafish models. Results show potential as a therapeutic molecule for novel drugs to treat mental diseases like schizophrenia.
Researchers studied how ecdysterone, a compound in Blume, can improve cognitive dysfunction in conditions like Alzheimer's by reducing oxidative stress through Nrf2 activation. This could lead to potential treatment options.
CA from and is a powerful antioxidant and anti-inflammatory compound that protects mitochondria in brain cells, potentially aiding in cytoprotection and mitochondrial renewal through Nrf2 activation and regulation of mitochondrial quality control pathways.
Researchers identified new compounds in Achyranthes bidentata seeds, potentially useful for treating various health conditions. Compound 23 showed promising acetylcholinesterase inhibitory activity, indicating potential therapeutic value. This study highlights the importance of using chemometric approaches for phytochemical exploration.