Neuroscience Studies

Zhi Zi Chi decoction (Gardeniae fructus and semen Sojae Praeparatum) attenuates anxious depression via modulating microbiota-gut-brain axis in corticosterone combined with chronic restraint stress-induced mice.

The researchers investigated how a traditional herbal formula called Zhi Zi Chi decoction (ZZCD) regulates the microbiota-gut-brain axis in treating anxious depression. Understanding these mechanisms could lead to improved treatments for neuropsychiatric disorders.

GastroenterologyNeuroscience Gardenia jasminoides
Tian X et al (2023).
CNS Neurosci Ther.
DOI:
10.1111/cns.14519
PubMed:
37905694

The Effect of a Turkey Berry (Solanum torvum)-Fortified Biscuit on the Hemoglobin Level and Cognitive Performance of Adolescent Females in the Ahafo Region of Ghana: A Pilot Study.

In this pilot study, fortified biscuits were given to adolescent females in Ghana. The study found that the intervention group had a decrease in anemia cases and improved cognitive performance. This suggests that the turkey berry-fortified biscuits could potentially manage anemia and improve cognition.

Neuroscience Solanum torvum
Appiah AO et al (2023).
Int J Food Sci.
DOI:
10.1155/2023/1388782
PubMed:
37901683

Bioactive strawberry fruit (Arbutus unedo L.) extract remedies paraquat-induced neurotoxicity in the offspring prenatally exposed rats.

Researchers investigated the therapeutic effects of L. aqueous extract against neurotoxicity caused by paraquat exposure. This study is important for understanding potential treatments for paraquat-induced neurological deficits.

Neuroscience Arbutus unedo
Ait Lhaj Z et al (2023).
Front Neurosci.
DOI:
10.3389/fnins.2023.1244603
PubMed:
37901424

In Vitro Antioxidant and Inhibitory Study of Picrorhiza kurroa (Kutki), Syzygium aromaticum (Loung), Lawsonia inermis (Henna), Rheum emodi (Revand Chini), Curcuma longa (Haldi) Against Lipid Per-Oxidation in Mice Brain and Liver.

This study evaluated the antioxidant and protective properties of certain medicinal plants against oxidative stress in the brain and liver. , , and showed strong effects and could potentially help manage or prevent degenerative diseases.

ImmunologyNeuroscience Curcuma longaLawsonia inermisPicrorhiza kurroaRheum emodiSyzygium aromaticum
Hassan F et al (2023).
Dose Response.
DOI:
10.1177/15593258231210431
PubMed:
37900620

Antidepressant-like effects of the Punica granatum and citalopram combination are associated with structural changes in dendritic spines of granule cells in the dentate gyrus of rats.

Combining a phytoestrogens-enriched extract with citalopram (CIT) at sub-optimal doses resulted in an increased antidepressant-like effect and neuroplasticity in rats. This suggests a potential alternative therapy for reducing depressive symptoms in menopause.

Neuroscience Punica granatum
Vega-Rivera NM et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1211663
PubMed:
37900157

A network pharmacology approach to explore pharmacological mechanisms of Asparagus racemosus for ameliorative effect in epilepsy and comorbid progressive memory dysfunction.

Network pharmacology was used to determine the mechanism of action of a specific herb's ameliorative effects on epilepsy and memory dysfunction. This information is important for understanding the medicinal potential of the herb and informing appropriate treatment decisions.

Neuroscience Asparagus racemosus
Kaur B et al (2023).
In Silico Pharmacol.
DOI:
10.1007/s40203-023-00169-x
PubMed:
37899966

Identification of Uncaria rhynchophylla in the Potential Treatment of Alzheimer's Disease by Integrating Virtual Screening and In Vitro Validation.

Gouteng shows potential for treating Alzheimer's by reversing tau hyperphosphorylation and offering neuroprotective effects, according to network pharmacology and molecular docking. Care should be taken as it may be a therapeutic option for AD.

Neuroscience Uncaria rhynchophylla
Jiang S et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242015457
PubMed:
37895137

Neuroprotective Properties of Berberine: Molecular Mechanisms and Clinical Implications.

Berberine (BBR), a natural compound found in certain plants, has various beneficial effects on the brain. It protects against oxidative stress, inflammation, and cell death, and regulates enzyme activity, neurotransmitter levels, and gut bacteria. By targeting multiple signaling pathways, BBR shows promise for neuroprotection.

Neuroscience Coptis chinensis
Tian E, Sharma G and Dai C (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12101883
PubMed:
37891961
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