This study compared the effects of computerized mindfulness meditation (MM) and cognitive training (CT) on inhibitory control (IC) in children and adolescents. CT improved cool IC, while MM improved hot IC. MM may have more benefits for emotional competence at a young age.
Garlic essential oil reduces dopamine/serotonin turnover rates, reverses depression in rats, inhibits inflammation, and promotes intestinal barrier function, potentially influencing depression-like behavior.
Gynostemma pentaphyllum extract shows promise in reducing cognitive impairment in Alzheimer's disease. A specific compound from the extract, NPLC0393, targets a protein called PPM1A, reducing inflammation and tau hyperphosphorylation, and improving communication between microglia and neurons.
Scientists found that Corynoxine B (Cory B), a natural alkaloid, enhances autophagy to promote clearance of abnormal protein aggregates in Parkinson's disease. Cory B binds to HMGB1/2, increases Beclin 1/VPS34 complex activity, and improves behavioral abnormalities in PD animal models, suggesting its neuroprotective potential.
A study discovered that APALE, derived from Phyllanthus amarus, can protect against neurotoxicity caused by PDc. It improves cognitive function, regulates antioxidants and GABA levels, and reduces neuroinflammation, suggesting its potential as a neurotoxicity treatment.
Hydroxysafflor yellow A (HSYA) in safflower may treat traumatic brain injuries, a critical condition with limited treatment options, leading to potential new therapies.
Isoalantolactone (LAT) found in Elecampane can alleviate symptoms of depression in mice, showing potential as an alternative treatment for the condition.
The effectiveness of the Qinzhizhudan Formula (QZZD) in treating vascular dementia (VD) is still unclear, requiring further research to understand its potential therapeutic effects and mechanism of action.